Association between Sarcopenia and Insulin-Like Growth Factor-1, Myostatin, and Insulin Resistance in Elderly Patients Undergoing Hemodialysis
Table 2
Geriatric profiles.
Variable
Total (n = 40)
Nonsarcopenia (n = 7)
Sarcopenia (n = 33)
value
BMI
Underweight (<18.5 kg/m2)
0 (0%)
0 (0%)
0 (0%)
0.010
Normal (18.5–22.9 kg/m2)
22 (55.0%)
2 (28.6%)
20 (60.6%)
Overweight (23–24.9 kg/m2)
11 (27.5%)
1 (14.3%)
10 (30.3%)
Obese (>25 kg/m2)
7 (17.5%)
4 (57.1%)
3 (9.1%)
MNA
Adequate nutritional status
8 (20%)
5 (71.4%)
3 (9.1%)
0.002
At risk of malnutrition
32 (80%)
2 (28.6%)
30 (90.9%)
Malnourished
0 (0%)
0(0%)
0(0%)
MMSE
Normal
31 (77.5%)
1 (14.3%)
8 (24.2%)
1.000
Mild cognitive impairment
9 (22.5%)
6 (85.7%)
25 (75.8%)
GDS
Normal
29 (72.5%)
6 (85.7%)
23 (69.7%)
0.650
Probable depression
11 (27.5%)
1 (14.3%)
10 (30.3%)
Depression
0 (0%)
0 (0%)
0 (0%)
ADL
Independent
26 (65%)
6 (85.7%)
20 (60.6%)
0.420
Mildly dependent
11 (27.5%)
1 (14.3%)
10 (30.3%)
Moderate dependent
3 (7.5%)
0(0%)
3 (9.1%)
PASE
Sedentary
31 (77.5%)
0 (0%)
31 (93.9%)
<0.001
Light activity
9 (22.5%)
7 (100%)
2 (6.1%)
Moderate to intense activity
0 (0%)
0 (0%)
0 (0%)
BMI, body mass index; MNA, mini nutritional assessment; MMSE, mini-mental state examination; GDS, geriatric depression scale; ADL, activity of daily living; PASE, physical activity scale examination. Significant at < 0.05. Comparisons of IGF-1, myostatin, and HOMA-IR in sarcopenia status group.
