Research Article

Effect of Plasminogen Activator Inhibitor-1 and Tissue Plasminogen Activator Polymorphisms on Susceptibility to Type 2 Diabetes in Malaysian Subjects

Table 1

Demographic and biochemical parameters among normal and type 2 diabetes mellitus with or without metabolic syndrome subjects.

ParametersNormal ( 𝑛 = 1 3 1 )Type 2 diabetes mellitus
Without MetS ( 𝑛 = 7 6 )With MetS ( 𝑛 = 2 2 7 )

Gender %
 Male/female34.6/65.456.6/43.442.7/57.3
Races %
 Malay52.347.449.8
 Chinese33.7523.714.5
 Indian13.7528.935.7
Age (years)49.1 ± 12.650.7 ± 9.051.9 ± 6.9
Body mass index (kg/m2)23.0 ± 3.823.7 ± 4.030.0 ± 4.2
Waist circumference (cm)79.9 ± 11.083.5 ± 10.398.9 ± 8.5
Diastolic blood pressure (mmHg)80.4 ± 9.079.8 ± 9.483.7 ± 10.3
Systolic blood pressure (mmHg)132 ± 18131 ± 18138 ± 18
Triglyceride (mmol/L)1.15 ± 0.561.55 ± 1.211.98 ± 1.25
High-density lipoprotein (mmol/L)1.57 ± 0.371.24 ± 0.311.17 ± 0.27
Fasting blood glucose (mmol/L)5.04 ± 0.518.55 ± 3.348.20 ± 3.15
Insulin (pmol/L)53.3 ± 35.589.4 ± 85.9150 ± 104
Insulin resistance (IR)1.00 ± 0.661.82 ± 1.683.00 ± 1.98

The result presented as mean ± standard deviation. MetS: metabolic syndrome. T: total.