Single Nucleotide Polymorphisms in Selected Apoptotic Genes and BPDE-Induced Apoptotic Capacity in Apparently Normal Primary Lymphocytes: A Genotype-Phenotype Correlation Analysis

Table 3

Comparisons of mean BPDE-induced apoptosis capacity in apparently normal primary lymphocytes by p53 diplotypes.

p53 diplotypes	No. (%)	AC (mean ± SD)	P value^(a)	P value^(b)
R-del-G
2 copies	81 (47.6)	177.57±159.94	Ref.
1 copy	74 (43.5)	220.39±197.21	.138
0 copy	15 (8.8)	307.90±235.37	.009	.016
R-ins-G
0 copy	116 (68.2)	190.05±174.57	Ref.
1 copy	49 (28.8)	238.99±197.24	.116
2 copies	5 (2.9)	310.86±311.47	.146	.094
P-ins-A
0 copy	143 (84.1)	202.33±179.92	Ref.
1 copy	25 (14.7)	215.43±215.45	.745
2 copies	2 (1.2)	496.07±121.26	.023	.154

(a)Two-sided Student t-test.(b)Trend test obtained from general linear regress model with adjustment for age and sex.