Retinoblastoma and the Genetic Theory of Cancer: An Old Paradigm Trying to Survive to the Evidence

Table 3

A meta-analysis of literature shows that within a total of 344 familial retinoblastoma, 83 (23%) showed the unilateral phenotype.

Author	uRB	bRB	Tot.	Fam. U	Fam. B	Tot. Fam.
Abramson	626	905	1531	36	150	186
Gunalp	441	195	636	10	24	34
Sanders	282	149	431	15	38	53
Matzunaga	403	196	599	11	17	28
Hadjistilianou	227	160	387	11	32	43
Tot.	1979	1605	3584	83	261	344
				(23%)	(77%)