Weight History, Smoking, Physical Activity and Breast Cancer Risk among French-Canadian Women Non-Carriers of More Frequent BRCA1/2 Mutations
Table 4
Multivariable adjusted odd ratios and 95%
confidence intervals for breast cancer risk in relation to BMI,
weight gain, smoking, and physical activity, by menopausal status.
Variable
Premenopausal
Postmenopausal
Cases/Controls OR (95% CI)
Cases/Controls OR (95% CI)
Current BMI (kg/m2)*
≤22.5
20/45
64/56
>22.5 and ≤26.0
30/47
1.37 ()
68/50
1.65
()
>26.0
27/43
1.02 ()
71/39
1.19
()
for trend
.56
.35
Weight gain (lbs) from the age of 30 to the age of 40
≤13
27/49
65/49
>13 and ≤25
25/40
1.55 ()
70/51
1.95
()
>25
25/46
1.62 ()
68/45
1.98 ()
for trend
.05
.03
Weight gain (lbs) from the age of 40 to the age of 50
≤13
66/52
>13 and ≤25
67/55
2.01 ()
>25
70/38
2.01 ()
for trend
.04
Weight gain (lbs) from the age of 50 to the age of 60
≤13
69/50
>13 and ≤25
71/47
1.86 ()
>25
63/48
1.79 ()
for trend
.03
Smoking (pack-years)
≤0
17/41
62/55
>0 and ≤9
31/45
1.30 ()
70/47
1.62
()
>9
29/49
1.63 ()
71/43
1.49 ()
for trend
.05
.04
Moderate physical activity (MET-hours/week)
≤10.7
25/40
69/45
>10.7 and ≤24.8
32/47
0.57 ()
60/53
0.65
()
>24.8
20/48
0.36 ()
74/47
0.42 ()
for trend
.02
.03
Vigorous physical activity (MET-hours/week)
≤0.11
27/43
68/50
>0.11 and ≤7.2
26/45
0.97 ()
62/47
1.05
()
>7.2
24/47
1.02 ()
73/48
0.99
()
for trend
.76
.95
Total physical activity (MET-hours/week)
≤16.2
26/44
67/49
>16.2 and ≤33.2
25/46
0.70 ()
70/52
0.65
()
>33.2
26/45
0.63 ()
66/44
0.89 ()
for trend
.05
.05
at interview. for age,
education, physical activity, smoking, alcohol consumption, and total energy
intake. for age,
education, physical activity, alcohol consumption, and total energy intake. for age,
education, alcohol consumption, smoking, and total energy intake.
