Research Article

Serum Lipids and the Risk of Gastrointestinal Malignancies in the Swedish AMORIS Study

Table 1

Baseline characteristics of study population.

Oesophageal cancer
( 𝑛 = 3 1 8 )
Stomach cancer
( 𝑛 = 7 7 6 )
Colon cancer
( 𝑛 = 2 4 7 2 )
Rectal cancer
( 𝑛 = 1 5 1 0 )
All
( 𝑛 = 5 4 0 3 0 9 )

Age
 Mean (SD)55.75 (10.46)57.83 (11.80)57.93 (11.60)56.75 (10.82)43.84 (13.83)
Gender
 Male234 (73.58)497 (64.05)1375 (55.62)938 (62.12)290294 (53.73)
 Female84 (26.42)279 (35.95)1097 (44.38)572 (37.88)250015 (46.27)
Socioeconomic status
 White collar110 (34.59)248 (31.96)915 (37.01)577 (38.21)200231 (37.06)
 Blue collar154 (48.43)372 (47.94)1059 (42.84)700 (46.36)256413 (47.46)
 Not gainfully employed or  missing54 (16.98)156 (20.10)498 (20.15233 (15.43)83665 (15.48)
Mean follow-up time (year)8.09 (4.73)7.62 (4.68)8.50 (4.67)8.53 (4.54)12.31 (4.13)
Fasting status
 Fasting183 (57.55)473 (60.95)1534 (62.06)953 (63.11)298337 (55.22)
 Not fasting15 (4.72)48 (6.19)147 (5.95)96 (6.36)78318 (14.50)
 Missing120 (37.74)255 (32.86)791 (32.00)461 (30.53)163654 (30.29)
Glucose (mmol/L)
 Mean (SD)5.49 (2.07)5.36 (1.81)5.27 (1.50)5.26 (1.56)4.97 (1.25)
Total cholesterol (mmol/L)
 Mean (SD)5.90 (1.17)6.00 (1.26)6.05 (1.16)6.11 (1.17)5.55 (1.16)
Triglycerides (mmol/L)
 Mean (SD)1.72 (1.37)1.48 (0.94)1.49 (0.95)1.47 (1.03)1.31 (0.99)
LDL cholesterol (mmol/L)a
 Mean (SD)3.40 (1.15)3.90 (1.11)3.88 (1.03)3.93 (1.05)3.59 (1.08)
HDL cholesterol (mmol/L)a
 Mean (SD)1.49 (0.42)1.52 (0.45)1.55 (0.48)1.57 (0.49)1.53 (0.44)
Apolipoprotein B (mmol/L)a
 Mean (SD)1.23 (0.35)1.33 (0.30)1.35 (0.34)1.33 (0.33)1.22 (0.34)
Apolipoprotein A-I (mmol/L)a
 Mean (SD)1.46 (0.22)1.43 (0.25)1.46 (0.25)1.46 (0.26)1.43 (0.23)
LDL/HDLa
 Mean (SD)2.76 (2.17)2.86 (1.27)2.84 (1.42)2.84 (1.48)2.68 (1.59)
Total cholesterol/HDLa
 Mean (SD)4.04 (1.69)4.37 (1.68)4.39 (1.87)4.38 (1.95)4.15 (2.13)
Triglycerides/HDLa
 Mean (SD)1.81 (3.93)1.18 (1.12)1.25 (1.32)1.21 (1.28)1.16 (1.74)
ApoB/ApoA-Ia
 Mean (SD)0.86 (0.28)0.96 (0.26)0.96 (0.31)0.94 (0.30)0.88 (0.30)
BMI (kg/m2)b
 <18.53 (6.82)2 (1.77)6 (1.58)1 (0.43)1608 (1.80)
 18.5–2517 (38.64)54 (47.79)196 (51.58)123 (52.34)52509 (58.90)
 25–3020 (45.45)40 (35.40)139 (36.58)85 (36.17)28339 (31.79)
 ≥304 (9.09)17 (15.04)39 (10.26)26 (11.06)6697 (7.51)

aMeasured in Subcohort B.
bMeasured in Subcohort A.