Table of Contents Author Guidelines Submit a Manuscript
Journal of Cancer Epidemiology
Volume 2013, Article ID 408460, 6 pages
Research Article

Patterns of Pelvic Radiotherapy in Patients with Stage II/III Rectal Cancer

1Leo Jenkins Cancer Center, 600 Moye Boulevard, Greenville, NC 27834, USA
2Division of Surgical Oncology, East Carolina University Brody School of Medicine, 600 Moye Boulevard Room 4s24 Greenville, NC 27834, USA
3Lineberger Comprehensive Cancer Center, University of North Carolina, 101 Manning Drive Chapel Hill, NC 27514, USA

Received 5 June 2013; Revised 29 August 2013; Accepted 30 August 2013

Academic Editor: P. Vineis

Copyright © 2013 Timothy L. Fitzgerald et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


High-level evidence supports adjuvant radiotherapy for rectal cancer. We examined the influence of sociodemographic factors on patterns of adjuvant radiotherapy for resected Stage II/III rectal cancer. Methods. Patients undergoing surgical resection for stage II/III rectal cancer were identified in SEER registry. Results. A total of 21,683 patients were identified. Majority of patients were male (58.8%), white (83%), and with stage III (54.9%) and received radiotherapy (66%). On univariate analysis, male gender, stage III, younger age, year of diagnosis, and higher socioeconomic status (SES) were associated with radiotherapy. Radiotherapy was delivered in 84.4% of patients 50; however, only 32.8% of those are 80 years. Logistic regression demonstrated a significant increase in the use of radiotherapy in younger patients who are 50 (OR, 10.3), with stage III (OR, 1.21), males (OR, 1.18), and with higher SES. Conclusions. There is a failure to conform to standard adjuvant radiotherapy in one-third of patients, and this is associated with older age, stage II, area-level of socioeconomic deprivation, and female sex.