Cancer Incidence and Mortality in a Cohort of US Blood Donors: A 20-Year Study
Table 1
Characteristics of allogeneic donor study population with specimens in REDS repositories by cancer status—Blood Centers of the Pacific, 1991–2009 ( = 55,158).
Cancer cases
Donors without a cancer
= 4,236 (7.7%)
= 50,922 (92.3%)
First donation to repository (calendar year)
Median (range)
1992 (1991–2002)
1993 (1991–2002)
Last known BCP visit (calendar year)
Median (range)
1996 (1991–2009)
1997 (1991–2009)
Calendar year of cancer diagnosis
Median (range)
2003 (1991–2009)
—
Sex, (%)*
Female
1,900 (44.9)
25,065 (49.2)
Age at first donation in years, (%)*
18–49
2,664 (62.9)
45,811 (90.0)
50–75
1,055 (24.9)
3,815 (7.5)
76 +
517 (12.2)
1,296 (2.6)
Mean (SD)
49.9 (12.3)
38.2 (11.9)
Race, (%)*
White
3,724 (87.9)
41,662 (81.8)
Education, (%)∧
College degree or higher
830 (19.6)
11,595 (22.8)
ABO blood group, (%)
Type O
2,039 (48.14)
24,341 (47.8)
Donation type
Whole blood, RBC, (%)
4,107 (97.0)
49,855 (97.9)
Duration of donor activity, (%)**
More than 3 years
2,279 (53.8)
25,504 (50.1)
Median (IQR)
3.7 (0.6–9.3)
3.1 (0.2–9.9)
Total number of blood donations, (%)*
>4 donations
2,329 (55.0)
24,207 (47.5)
Median (IQR)
6 (2–15)
4 (1–12)
Number of donated specimens to the repositories
Median (IQR)
1 (1-2)
1 (1-2)
Study followup time in years*
Median (IQR)
9.8 (5.4–13.7)
16.9 (15.6–18)
, , ∧education information is missing for 60% of donors.
