Cancer Incidence and Mortality in a Cohort of US Blood Donors: A 20-Year Study
Table 3
Standardized incidence ratio (SIR) by sex and cancer site, allogeneic blood donors with more than one year of followup, Blood Centers of the Pacific, 1991–2009 ( = 54,982).
SIR
95% CI
Males
Oral cavity and pharynx
1.19
0.92
1.52
Digestive
1.24
1.10
1.38
Respiratory
0.93
0.79
1.08
Skin
2.19
1.89
2.53
Male genital
2.48
2.32
2.63
Urinary
1.15
0.97
1.37
Brain and nervous
1.55
1.11
2.10
Endocrine
0.78
0.47
1.21
Lymphoma
1.42
1.18
1.69
Myeloma
2.11
1.45
2.96
Leukemia
2.14
1.70
2.66
Other
1.45
1.16
1.78
Females
Oral cavity and pharynx
1.01
0.60
1.60
Digestive
1.67
1.45
1.90
Respiratory
1.48
1.25
1.74
Skin
1.77
1.48
2.11
Breast
1.79
1.66
1.92
Female genital
1.50
1.32
1.70
Urinary
1.16
0.84
1.55
Brain and nervous
1.59
1.05
2.31
Endocrine
0.91
0.70
1.16
Lymphoma
1.72
1.39
2.12
Myeloma
1.79
1.02
2.90
Leukemia
1.33
0.88
1.92
Other
1.68
1.23
2.24
SIR was calculated using nine SEER registries age-adjusted, sex-, and age-specific incidence rates for years 1992–2009. Other includes: mesothelioma, Kaposi sarcoma, eye & orbit, bone, soft tissue, miscellaneous (SEER site recode ICD-O-3 definition).
