Research Article
Breast Cancer Pathology, Receptor Status, and Patterns of Metastasis in a Rural Appalachian Population
Table 4
Patterns of metastatic spread by lymph node status and tumor grade in women with triple-negative and other breast cancers.
| | |
No metastases
at followup |
Distant
metastatic sites | | | Bone | Visceral |
| | Triple-negative (TN) | | | | | Lymph nodea | | | | | (i) Positive | 25 (24.3) | 3 (50.0) | 15 (68.2) | | (ii) Negative | 78 (75.7) | 3 (50.0) | 7 (31.8) | | Other breast cancers | | | | | Lymph node | | | | | (i) Positive | 99 (20.9) | 14 (38.9) | 12 (38.7) | | (ii) Negative | 375 (79.1) | 22 (61.1) | 19 (61.3) | | P value | 0.610 | 0.454 | 0.033 |
| | Triple-negative | | | | | Tumor gradeb | | | | | 1 | 7 (6.5) | 0 | 0 | | 2 | 20 (18.7) | 2 (33.3) | 2 (9.1) | | 3 | 80 (74.8) | 4 (66.7) | 20 (90.9) | | Other breast cancers | | | | | Tumor grade | | | | | 1 | 66 (16.3) | 1 (2.9) | 3 (10.7) | | 2 | 155 (38.2) | 10 (29.4) | 5 (17.9) | | 3 | 185 (45.5) | 23 (67.7) | 20 (71.4) | | value | <0.0001 | 0.839 | 0.092 |
|
|
Nodal status not tested in 16 cases.
Tumor grading unavailable in 95 cases.
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