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Journal of Cancer Epidemiology
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Journal of Cancer Epidemiology
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2014
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Article
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Tab 2
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Research Article
Cancer Risks for Relatives of Children with Cancer
Table 2
Number of observed (O) and expected cancers (E) and standardised incidence ratios (SIR) and 95% confidence interval (95% CI) for cancer risk for relatives of proband.
Relationship to proband
O
E
SIR
95% CI
First-degree
28
19.8
1.45
0.98–2.21
Male
10
10.3
0.97
0.51–1.99
Female
18
8.9
2.00
1.26–3.39
Parents
25
18.7
1.36
0.93–2.08
Fathers
8
9.7
0.82
0.40–1.86
Mothers
17
8.4
2.00
1.27–3.33
Siblings
3
1.0
2.93
0.93–14.1
Second-degree
325
375.9
0.86
0.77–0.97
Male
163
208.4
0.78
0.67–0.91
Female
162
167.6
0.97
0.84–1.12
Grandparents
258
318.0
0.81
0.72–0.92
Grandfathers
144
183.2
0.79
0.67–0.92
Grandmothers
114
134.9
0.85
0.71–1.01
Uncles and Aunts
67
57.9
1.16
0.90–1.52
Uncles
19
25.2
0.75
0.46–1.32
Aunts
48
32.7
1.47
1.11–1.99