Journal of Cancer Epidemiology / 2014 / Article / Tab 2 / Research Article
Characterization of Pediatric Acute Lymphoblastic Leukemia Survival Patterns by Age at Diagnosis Table 2 Hazard risk of mortality associated with age at diagnosis in pediatric ALL patients (1973–2009 SEER dataset) in an univariable Cox proportional hazard model.
Variables Hazard ratio (HR) 95% C.I. Age at diagnosis (yrs) <1 1.00 — Reference 1–4 0.18 0.15, 0.20 <0.0001 5–9 0.26 0.22, 0.30 <0.0001 10–14 0.44 0.38, 0.51 <0.0001 15–19 0.69 0.59, 0.80 <0.0001 Sex Female 1.00 — Reference Male 1.29 1.20, 1.39 <0.0001 Race Caucasian 1.00 — Reference AA 1.44 1.27, 1.62 <0.0001 Primary tumor sites 1 1.00 — Reference ≥2 1.18 0.92, 1.52 0.1950 Immunophenotype T-cell 1.00 — Reference B-cell, B-precursor 0.57 0.49, 0.65 <0.0001 Radiation No 1.00 — Reference Yes 1.66 1.53, 1.79 <0.0001 Year of diagnosis 1973–1977 1.00 — Reference 1978–1982 0.70 0.61, 0.80 <0.0001 1983–1987 0.56 0.49, 0.65 <0.0001 1988–1992 0.38 0.33, 0.44 <0.0001 1993–1997 0.32 0.28, 0.36 <0.0001 1998–2002 0.29 0.26, 0.33 <0.0001 2003–2007 0.24 0.21, 0.27 <0.0001 2008-2009 0.19 0.14, 0.25 <0.0001
C.I.: confidence interval.