Research Article

Non-Small-Cell Lung Cancer Clinicopathologic Features and Survival Outcomes in Asian Pacific Islanders Residing in the United States: A SEER Analysis

Table 3

Multivariate Cox proportional analysis used to ascertain the contributions of the demographic, clinicopathologic, and treatment features to the DSS among the different AJCC stages.

CharacteristicsStage IStage IIStage IIIaStage IIIbStage IV
HRHRHRHRHR

Grade
 Grade IReferentReferentReferentReferentReferent
 Grade II1.589P < 0.011.15P < 0.011.049P > 0.051.482P < 0.011.24P < 0.01
 Grade III1.836P < 0.011.348P < 0.011.208P < 0.011.507P < 0.011.467P < 0.01
 Grade IV1.884P < 0.011.426P < 0.011.346P < 0.011.27P > 0.051.525P < 0.01
Histology
 Squamous cell/transitional cell Ca.ReferentReferentReferentReferentReferent
 Adenocarcinoma in situ AIS0.642P < 0.010.739P < 0.010.623P < 0.010.539P < 0.050.739P < 0.01
 Nonadenocarcinoma in situ0.928P < 0.050.966P > 0.050.887P < 0.010.956P > 0.050.935P < 0.01
 Large cell carcinoma1.088P > 0.051.079P > 0.050.927P > 0.051.049P > 0.051.05P > 0.05
 Others0.896P < 0.050.983P > 0.050.906P < 0.010.952P > 0.051.05P < 0.05
Age grouping
 <30ReferentReferentReferentReferentReferent
 30–391.252P > 0.052.795P > 0.051.332P > 0.050.879P > 0.051.04P > 0.05
 40–491.992P > 0.053.091P > 0.051.477P > 0.051.298P > 0.051.111P > 0.05
 50–592.091P > 0.053.257P > 0.051.426P > 0.051.354P > 0.051.215P > 0.05
 60–692.28P > 0.053.455P > 0.051.535P > 0.051.338P > 0.051.28P > 0.05
 70–792.639P > 0.054.077P < 0.051.726P > 0.051.486P > 0.051.409P > 0.05
 80+3.025P > 0.055.14P < 0.052.083P > 0.051.795P > 0.051.626P < 0.05
Gender
 MaleReferentReferentReferentReferentReferent
 Female0.833P < 0.010.831P < 0.010.845P < 0.010.8P < 0.010.854P < 0.01
Birth country
 United StatesReferentReferentReferentReferentReferent
 Outside the United States0.86P < 0.010.915P > 0.050.8P < 0.010.825P < 0.050.875P < 0.01
Marital status
 SingleReferentReferentReferentReferentReferent
 Married0.874P < 0.010.915P < 0.050.887P < 0.010.771P < 0.010.842P < 0.01
 Others1.012P > 0.051.001P > 0.050.969P > 0.050.922P > 0.050.968P > 0.05
Races
 Non-Hispanic whitesReferentReferentReferentReferentReferent
 Hispanics0.916P > 0.050.966P > 0.051.059P > 0.051.019P > 0.051.023P > 0.05
 Blacks0.954P > 0.051.043P > 0.050.972P > 0.051.026P > 0.050.969P > 0.05
 Asians and Pacific Islander0.775P < 0.010.791P < 0.010.939P > 0.051.03P > 0.050.858P < 0.01
Radiation
 Radiation not receivedReferentReferentReferentReferentReferent
 Radiation received0.693P < 0.010.623P < 0.010.586P < 0.010.651P < 0.010.917P < 0.01
Cancer directed surgery
 Not performedReferentReferentReferentReferentReferent
  Performed0.231P < 0.010.282P < 0.01

HR: hazard ratio; : value; Ca.: carcinoma.