Research Article

Genetic and Clinical Features of Medullary Thyroid Carcinoma: The Experience of a Single Center in Costa Rica

Table 2

Comparison of neoplastic behaviors in patients with MTC according to RET mutation status.

RET mutation ()Positive (5)Negative (14)

Age at diagnosis (years)38.4 ± 20.254.6 ± 11.80.04
Tumor diameter (cm)1.48 ± 1.12.37 ± 1.60.61
Vascular invasion20%28.6%0.71
Nodal metastases at surgery60%57%0.66
Distant metastases20%14%0.87
Surgical reintervention because of MTC recurrence40%35.7%0.76

RET: REarranged during Transfection. MTC: medullary thyroid carcinoma.