Validity of Administrative Databases in Comparison to Medical Charts for Breast Cancer Treatment Data

Table 3

Odds ratios (ORs) and 95% confidence intervals (CIs) comparing agreement versus disagreement between medical records and administrative database information in women with invasive breast cancer for each treatment and its most common type.

	Radiotherapy; N = 2,375		Breast or chest wall radiation; N = 1,970		Chemotherapy; N = 2,292		FEC-D		Partial mastectomy^2; N = 2,396
	OR^1 (95% CI)	value	OR^1 (95% CI)	value	OR^1 (95% CI)	value	OR^1 (95% CI)	value	OR^1 (95% CI)	value
Age at diagnosis
50–59	1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)
60–69	1.41 (1.00–1.99)	0.0498	1.05 (0.82–1.35)	0.6960	1.06 (0.77–1.47)	0.7075	0.81 (0.52–1.26)	0.3512	0.81 (0.56–1.19)	0.2823
Year of diagnosis
2006	1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)
2007	1.59 (1.05–2.42)	0.0287	0.96 (0.69–1.34)	0.8100	0.87 (0.57–1.34)	0.5323	1.05 (0.54–2.06)	0.8859	0.93 (0.53–1.64)	0.8029
2008	1.81 (1.16–2.83)	0.0086	1.04 (0.73–1.49)	0.8168	1.94 (1.20–3.16)	0.0074	1.63 (0.80–3.32)	0.1763	0.67 (0.39–1.14)	0.1418
2009	3.72 (2.12–6.54)^3	<0.0001	0.99 (0.71–1.40)	0.9766	1.49 (0.96–2.33)	0.0765	1.37 (0.69–2.73)	0.3647	0.63 (0.37–1.07)	0.0869
TNM stage
I	1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)		1.00 (ref)
II/III	1.25 (0.87–1.80)	0.2191	0.99 (0.76–1.29)	0.9637	0.66 (0.48–0.91)	0.0108	1.43 (0.87–2.32)	0.1556	3.36 (2.27–4.99)	<0.0001

Note. Missing values were excluded from analyses. FEC-D, Fluorouracil, Epirubicin, Cyclophosphamide, Docetaxel. ¹Adjusted for all other variables in the table and treatment centre region. ²Results could not be computed for receipt of surgery overall, as there was limited variability. ³Test for trend .