Impact of Metabolic Syndrome Diagnosis and Its Treatment on Survival of Colorectal Cancer Patients

Table 2

Effect of metabolic syndrome and treatment on CRC survival.

Variable	Crude HR	95% CI	Adjusted HR	95% CI
MetS
No	Ref	-		-
Yes	0.89	0.57-1.38	1.01	0.64-1.59
ACEI use
No	Ref	-		-
Yes	2.06	1.19-3.56	1.46	0.89-2.38
Other anti-HTN
No	Ref	-		-
Yes	1.89	0.24-14.67	1.74	0.21-14.70
Metformin use
No	Ref	-		-
Yes	0.38	0.20 -0.71	0.46	0.25-0.84
Insulin use
No	Ref	-		-
Yes	1.28	1.09 -1.75	1.73	1.02-2.97
Statin use
No	Ref	-		-
Yes	0.42	0.25-0.74	0.58	0.30-0.97

MetS: metabolic syndrome. Adjusted for age, sex, and cancer stage and tumor differentiation, cancer treatment, BMI, alcohol, and smoking.