Research Article

Clinical presentation and outcomes in children with retinoblastoma managed at the Uganda Cancer Institute

Table 4

Bivariate and multivariate Cox regression of selected demographic and clinical characteristics for predictors of survival among children with retinoblastoma.

VariableCHR (95% CI)AHR (95% CI) value

Age group at first sign in months
 0 to 1211
 13 to 361.08 ()0.89 ()0.772
 Over 361.08 ()0.40 ()0.084
 Sex: Male1.04 ()1.12 ()0.769
Eye loss
 No11
 1 eye enucleated1.40 ()1.12 ()0.779
 Both eyes enucleated3.94 ()3.53 ()0.011
Metastatic spread
 No11
 Yes9.24 ()8.93 ()0.001
Lag time between first sign and UCI visit in months
 0 to 611
 7 and above0.18 ()0.10 ()0.001
Proptosis
 No11
 Yes1.65 ()1.35 ()0.535
Eye swelling
 No1
 Yes2.62 ()4.39 ()0.012
Eye reddening
 No11
 Yes1.65 ()0.36 ()0.036