H. S. Patel, H. D. Desai, "Synthesis of Some New Azetidinone Derivatives Containing Aryl Sulfonyloxy Group", Journal of Chemistry, vol. 1, Article ID 258752, 5 pages, 2004. https://doi.org/10.1155/2004/258752
Synthesis of Some New Azetidinone Derivatives Containing Aryl Sulfonyloxy Group
Some novel azetidinone derivatives containing aryl sulfonyloxy group have been prepared. The 4-sulfonyloxy aniline derivative (2) has been prepared by reaction of 4-nitro phenol (sodium salt) with N-acetyl sulfanilyl chloride (ASC) followed by hydrolysis by ethanolic HCl. This compound (2) undergoes facile condensation reaction with aromatic aldehydes to yield different Schiff’s bases (3a-h). Cyclocondensation of compounds (3a-h) with chloro acetyl chloride yields different 2-azetidinone derivatives (4a-h).
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