Synthesis and Studies of 1-[2-(Aryl Amino-2-Oxo Ethyl) Amino]-4-(N-Methyl Piperazino)-Benzene Derivatives

Abstract

1-[2-(Aryl Amino-2-Oxo Ethyl) Amino]-4-(N-Methyl Piperazino)-Benzene Derivatives were synthesized. The synthesized compounds were screened for their antibacterial activities against S.aures and E.coli by cup plat method. From screening result some compounds found highly active against both Gram-positive and Gram-negative bacteria while other compounds possess feeble to moderate activity.