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E-Journal of Chemistry
Volume 3 (2006), Issue 3, Pages 154-158

Estimation of Some Antiviral Drugs Using Tpooo as Analytical Reagent

P. Venkata Reddy and B. Sudha Rani

University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, India

Received 7 March 2006; Accepted 5 May 2006

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A simple and reproducible spectrophotometric method has been developed for the determination of two recent antiviral drugs namely Valacyclovir (drug A) and Famciclovir (drug B) in bulk and pharmaceutical dosage forms. The method is based on the extraction of the drugs into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 490 nm. The method was optimized using eight parameters.