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E-Journal of Chemistry
Volume 3, Issue 1, Pages 25-27
http://dx.doi.org/10.1155/2006/375721

Spectrophotometric Method for the Determination of Oxaliplatin in Pure and Dosage Forms

G. Srinubabu,1 D. Pundarika Rao,2 L. Sridhar,1 and J. V. L. N. Seshagiri Rao1

1University College of Pharmaceutical Sciences, Visakhapatnam-530003, India
2Department of Geo-engineering, College of Engineering, Andhra University, Visakhapatnam-530003, India

Received 2 October 2005; Accepted 23 January 2006

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A simple and reproducible spectrophotometric method has been developed for the estimation of Oxaliplatin in pure and dosage forms. The method is based on the reaction of the drug with 1, 10 Phenanthroline in presence of ferric chloride, which forms a blood red colored complex exhibiting maximum absorption at 520 nm.