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E-Journal of Chemistry
Volume 5, Issue 3, Pages 620-626

Synthesis, Physical Characterization and Biological Activity of Some Schiff Base Complexes

R. Rajavel, M. Senthil Vadivu, and C. Anitha

Department of Chemistry, Periyar University, Salem-636011, Tamilnadu, India

Received 21 December 2007; Accepted 23 February 2008

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Structural modification of organic molecule has considerable biological relevance. Further, coordination of a biomolecules to the metal ions significantly alters the effectiveness of the biomolecules. In view of the antimicrobial activity ligand [bis-(2-aminobenzaldehyde)] malonoyl dihydrazone], metal complexes with Cu(II), Ni(II), Zn(II) and oxovanadium(IV) have been synthesized and found to be potential antimicrobial agents. An attempt is also made to correlate the biological activities with geometry of the complexes. The complexes have been characterized by elemental analysis, molar conductance, spectra and cyclicvoltammetric measurements. The structural assessment of the complexes has been carried out based on electronic, infrared and molar conductivity values.