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E-Journal of Chemistry
Volume 6, Issue 3, Pages 673-680
http://dx.doi.org/10.1155/2009/196309

Synthesis, Antibacterial and Antifungal Activities of s Derivatives

B. B. Baldaniya and P. K. Patel

Department of Chemistry, M. G. Science Institute, Navarangpura, Ahmedabad-380 009, Gujarat, India

Received 10 November 2008; Accepted 15 January 2009

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Several -{4-[(3-chloro-4-fluorophenyl) amino]-6-[(-aryl) amino] -1, 3, 5-triazin-2-yl} isonicotinohydrazides (6a-r) and N2-(Aryl)-N4, N6-dipyrimidin-2-yl-1,3,5-triazine-2,4,6-triamines (4a-o) were prepared. All newly synthesized compounds have been tested for their antibacterial activity against gram (+)ve and gram (-)ve bacteria and also on different strains of fungi. Introduction of -OH, -OCH3, -NO2, -Cl and -Br groups to the heterocyclic frame work enhanced antibacterial and antifungal activities.