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E-Journal of Chemistry
Volume 6 (2009), Issue 2, Pages 371-376

Synthesis, Characterization and Antimicrobial Activity of Metal Chelates of 5-[1(H)-Benzotriazole methylene]-8-quinolinol

H. S. Patel and K. K. Oza

Department of Chemistry, Sardar Patel University, Gujarat, India

Received 26 June 2008; Accepted 20 August 2008

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


5-Chloromethyl-8-quinolinol was condensed stoichiometrically with benzotriazole in presence of potassium carbonate. The resulting 5-[1(H)-benzo triazole methylene]-8-quinolinol (BTMQ) was characterized by elemental analysis and spectral studies. The transition metal chelates viz. Cu2+, Ni2+, Co3+, Mn2+ and Zn2+ of BTMQ were prepared and characterized by metal-ligand (M:L) ratio, IR and reflectance spectral studies and magnetic properties. The antifungal activity of BTMQ and its metal chelates was screened against various fungi. The results show that all these samples are good antifungal agents.