Journal of Chemistry

Journal of Chemistry / 2009 / Article

Open Access

Volume 6 |Article ID 254747 | 6 pages | https://doi.org/10.1155/2009/254747

Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide

Received13 Aug 2008
Revised14 Sep 2008
Accepted18 Sep 2008

Abstract

Synthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide and N-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4-methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant results

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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