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Synthesis of Multi-substituted 4,5-Dihydrofuran Derivatives from (S)-Limonene and 1,3-Dicarbonyl Compounds and their Biological Activities
E. Findik
,1 A. Dingil,1 I. Karaman,2 Y. Budak,1 and M. Ceylan11Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University-60250, Tokat, Turkey
2Department of Biology, Faculty of Arts and Sciences, Gaziosmanpasa University-60250, Tokat, Turkey
Abstract
Multi-substituted 4,5-dihydrofuran derivatives were regioselectively synthesized by the reaction of α-carbo radical produced from 1,3-dicarbonyl compounds by oxidation with Mn(OAc)3 in Acetic acid and S-(-)-limonene. All the compounds were tested for their antibacterial and antifungal activities by the disc-diffusion technique.
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Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
