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E-Journal of Chemistry
Volume 6 (2009), Issue 1, Pages 183-188
http://dx.doi.org/10.1155/2009/369569

Vibrational Dynamics of the Diterpene-Neoandrographolide

P. K. Singh, Tanveer Hasan, and Neeraj Misra

Department of Physics, Lucknow University-226007, India

Received 22 October 2007; Revised 31 July 2008; Accepted 10 September 2008

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A complete normal coordinate analysis was performed for neoandrographolide in terms of the calculation by using Wilson’s G-F matrix method and Urey Bradley force field. Andrographis paniculata has been reported for its potent hepatoprotective. Andrographis paniculata has been reported to have antisecretory (antidiarrhoeal), immunostimulant, antimalarial, antifilarial activity. It is also reported to have anticancer, anti HIV, anti-inflammatory, hypotensive action. In addition, it has found to be effective in myocardial infraction.