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E-Journal of Chemistry
Volume 6 (2009), Issue 1, Pages 196-200

Synthesis and Antimicrobial Activity of SomeNovel Benzimidazolyl Chalcones

B. A. Baviskar,1 Bhagyesh Baviskar,3 M. R. Shiradkar,2 U. A. Deokate,1 and S. S. Khadabadi1

1Department of Pharmaceutical Chemistry, Government College of Pharmacy, Amravati -444 604, (M.S.), India
2Sai Advantium Pharma Ltd., Hydrabad -500034, (A.P.), India
3SPDM Art, Science, Commers College, Shirpur (M.S), India

Received 12 May 2008; Accepted 19 July 2008

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Some novel benzimidazolyl chalcones were synthesized by condensation of N-(4-(1H-benzo[d]imidazol-2-yl)phenyl)acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the synthesized compounds were characterized on the basis of their IR, 1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method.