Table of Contents Author Guidelines Submit a Manuscript
E-Journal of Chemistry
Volume 7 (2010), Issue 3, Pages 1085-1089

Conformational Studies on γ - Benzyl- L- Glutamate and L- Valine Containing Block Copolypeptides

Ajay Kumar

Guru Tegh Bahadur Institute of Technology, G-8 Area, Rajouri Garden, New Delhi-110064, India

Received 22 October 2009; Accepted 15 December 2009

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Conformational studies on γ - benzyl-L- glutamate and L- valine containing block copolypeptides are reported using IR and CD spectra. The block copolypeptides contain valine block in the center and on both sides of the valine are γ - benzyl- L- glutamate blocks. The changes in conformation with increase in chain length of γ - benzyl- L- glutamate blocks are observed. When the chain length of γ - benzyl-L- glutamate block is 13, the block copolypeptide crystallized into beta conformation. With increase in chain length of γ - benzyl-L- glutamate block from 13 to 30 the conformation of the copolypeptide changes from beta sheet to alpha helix, but small amount of beta component also remains. With further increase in chain length of γ - benzyl- L- glutamate block from 30 to 45 the copolypeptide crystallizes exclusively into alpha helix conformation.