Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 418279 | https://doi.org/10.1155/2010/418279

Rakesh Choure, K. S. Pitre, "Polarographic Analysis of Structurally Modified Paracetamol", Journal of Chemistry, vol. 7, Article ID 418279, 6 pages, 2010. https://doi.org/10.1155/2010/418279

Polarographic Analysis of Structurally Modified Paracetamol

Received25 Dec 2009
Revised20 Mar 2010
Accepted21 Apr 2010

Abstract

Paracetamol is an analgesic drug. Its potency may be increased by modifying the drug by way of molecular modification. In the present study the drug has been modified by its complex formation with methanol and other organic compounds. The drug organic compound interaction has been studied using differential pulse polarography and direct current polarography. In Britton Robinson buffer as supporting electrolyte of pH 7.2±0.1, paracetamol produced a well defined peak at -1.18v and it’s modified forms at relatively higher negative value. The change in peak potential and lowering in peak height indicating drug organic compound complex formation.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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