Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 570736 | 6 pages | https://doi.org/10.1155/2010/570736

Isolation and Characterization of Phenolic Glycoside from the Bark of Symplocos RacemosaRoxb

Received16 Apr 2010
Accepted02 Jun 2010

Abstract

A new phenolic glycoside, 3, 5 - dihydroxy - 2- (hydroxyl methyl) - 6-(3,4,5-trimethoxy phenoxy)tetrahydro-2H-pyran-4-yl, 4-hydroxy-3-methoxy benzoate have been isolated from the dried bark of Symplocos racemosa. The structure was identified by extensive spectral analysis, especially FT-IR, GC-MS, 1H NMR and 13C NMR techniques. The method of isolation was simple, cost effective and efficient. The preliminary bioactivity of the compound was also evaluated. The ethanolic extract of Symplocos racemosa (EESR) was investigated for its anti-pyretic activity against brewer’s yeast induced pyrexia. The antipyretic effect of EESR (measured as % reduction in body temperature) was compared with paracetamol (100 mg/kg, orally). EESR in dose of 200 mg/kg caused significant decrease in body temperature of rats. This study has established the antipyretic activity of Symplocos racemosaand thus, justifies the ethnic uses of the plant.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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