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E-Journal of Chemistry
Volume 7, Issue 1, Pages 1-5

Antioxidant and Hypolipidemic Effect of Plumeria Rubra L. in Alloxan Induced Hyperglycemic Rats

A. John Merina,1 D. Sivanesan,2 V. Hazeena Begum,2 and N. Sulochana3

1Department of Chemistry, Govt. College for Women, Kumbakonam, India
2Department of Siddha Medicine, Tamil University, Thanjavur, India
3Department of Chemistry, Regional Engineering College, Trichy, India

Received 13 October 2008; Accepted 22 December 2008

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Antioxidant and hypolipidemic activity of the flovone glycoside isolated from Plumeria rubra L. was carried in alloxan induced hyperglycemic rats. The flavonoid treatment produced a significant reduction in the level of serum triglycerides, while there was no reduction in the serum cholesterol and glucose. Antioxidant activity of the drug was also confirmed through in vitro studies.