Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 582710 |

Javed I. Sheikh, H. D. Juneja, V. N. Ingle, "A Computational Approach towards the Development of Newer Anticancer Agents", Journal of Chemistry, vol. 7, Article ID 582710, 4 pages, 2010.

A Computational Approach towards the Development of Newer Anticancer Agents

Received10 Jan 2009
Accepted05 Mar 2009


In silico molecular docking analyses of the novel 1-(2', 4'-dihydroxy-5'-chlorophenyl)-3-aryl-propane-1, 3-diones were performed in the active sites of enzyme cytochrome P450 reductase to obtain new anticancer agents computationally. 1-(2', 4'-dihydroxy-5'-chlorophenyl)-3-(4"-methoxy-phenyl)-propane-1, 3-dione (3f) was found to have maximum affinity for the active sites of enzyme.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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