Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 637549 |

Makhloufia Mohammed, BenaÏssa Tahar, Derdour AÏcha, Henni Djamel Eddine, "Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate", Journal of Chemistry, vol. 7, Article ID 637549, 6 pages, 2010.

Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate

Received21 Jan 2010
Accepted21 Mar 2010


A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 μg/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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