Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 653934 | 5 pages | https://doi.org/10.1155/2010/653934

UV Spectrophotometric Estimation of Levoceterizine Dihydrochloride in Bulk and Dosage Form

Received18 Apr 2010
Accepted10 Jun 2010

Abstract

A new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for the determination of levoceterizine dihydrochloride (LCTZ) in bulk drug and tablet dosage form. Levoceterizine dihydrochloride exhibited maximum absorbance at 232 nm with apparent molar absorptivity of 1.5104×104 in double distilled water. Beer's law was found to be obeyed in the concentration range of 4-20 µg mL-1. Correlation coefficient was found to be 0.9998. Results of the analysis were validated statistically and by recovery studies. The proposed method is useful for the routine estimation of LCTZ in bulk and tablet dosage form.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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