Journal of Chemistry

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Volume 7 |Article ID 731675 | 3 pages | https://doi.org/10.1155/2010/731675

Synthesis and Anti-Inflammatory Activity of Pyrazolines

B. Ramesh 1 and T. Sumana1

1Department of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India

Received19 Aug 2009
Accepted10 Oct 2009

Abstract

Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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