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E-Journal of Chemistry
Volume 7 (2010), Issue 2, Pages 514-516
http://dx.doi.org/10.1155/2010/731675

Synthesis and Anti-Inflammatory Activity of Pyrazolines

B. Ramesh and T. Sumana

Department of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India

Received 19 August 2009; Accepted 10 October 2009

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.