Abstract
A facile microwave assisted one-pot synthetic protocol has been devised for the synthesis of 3,3'-(alkanediyl) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2a-c), 3,3'-(1,4-phenylene) bis (1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2d),3,3'-(alkanediyl) bis (7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-ones (2e-g) and 3,3'-(1,4-phenylene) bis(7,7-dimethyl-1-phenyl-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one (2h) by the cyclocondensation of cyclic enaminones 1a, b with diamines and formaldehyde.