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E-Journal of Chemistry
Volume 7, S1, Pages S372-S376
Research Article

Synthesis of 1,4-Dihydropyridine Derivatives Under Aqueous Media

Adeleh Moshtaghi Zonouz and Nahid Sahranavard

Chemistry Department Faculty of Science; Azarbaijan University of Tarbiat moallem, Tabriz, Iran

Received 26 February 2010; Accepted 20 April 2010

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An environmental friendly synthesis of 1,4-dihydropyridine derivatives was developed by the one-pot reaction of aldehydes, ethyl acetoacetate and ammonia in water under refluxing conditions.