Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 937903 | 5 pages | https://doi.org/10.1155/2010/937903

Synthesis and Antimicrobial Activity of Some Aldehyde Derivatives of 3-Acetylchromen-2-one

Received11 Mar 2010
Accepted05 May 2010

Abstract

Some new 3-(substituted)-chromen-2-one have been synthesized by condensation of 3-acetylchromen-2-one with various aromatic aldehyde in presence of ethanol and alkali. The synthesized compounds were identified by spectral data and screened for their antibacterial activity against B. pumilis, B. substilis and E. coli and antifungal activity against A. niger and Candida albicans. Among the synthesized compounds, some compounds of aryl chromen, which are having electron releasing substituent such as methoxy and hydroxyl at various positions, showed moderate to considerable antibacterial and antifungal activities.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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