Vishnu Vats, R. K. Upadhyay, Prathibha Sharma, "Synthesis and Antifungal Activity of 2-Ketophenyl-3-substituted aryl-1-thiazolidin-4-ones", Journal of Chemistry, vol. 7, Article ID 979353, 5 pages, 2010. https://doi.org/10.1155/2010/979353
Synthesis and Antifungal Activity of 2-Ketophenyl-3-substituted aryl-1-thiazolidin-4-ones
A new series of 2-ketophenyl-3-substituted aryl-1- thiazolidin-4-ones were synthesized by cyclocondensation of ketoazomethines and thioglycolic acid. Ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) and various para-substituted anilines. Their structures were elucidated by elemental analysis, IR and H1 NMR; they were screened for their antifungal activity against hazardous fungi namely Fusarium Oxysporum, Pythium, Sclerotium and Alternaria brassicola.
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