Journal of Chemistry

Journal of Chemistry / 2010 / Article

Open Access

Volume 7 |Article ID 979353 |

Vishnu Vats, R. K. Upadhyay, Prathibha Sharma, "Synthesis and Antifungal Activity of 2-Ketophenyl-3-substituted aryl-1-thiazolidin-4-ones", Journal of Chemistry, vol. 7, Article ID 979353, 5 pages, 2010.

Synthesis and Antifungal Activity of 2-Ketophenyl-3-substituted aryl-1-thiazolidin-4-ones

Received05 Sep 2009
Revised11 Nov 2009
Accepted05 Jan 2010


A new series of 2-ketophenyl-3-substituted aryl-1- thiazolidin-4-ones were synthesized by cyclocondensation of ketoazomethines and thioglycolic acid. Ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) and various para-substituted anilines. Their structures were elucidated by elemental analysis, IR and H1 NMR; they were screened for their antifungal activity against hazardous fungi namely Fusarium Oxysporum, Pythium, Sclerotium and Alternaria brassicola.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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