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E-Journal of Chemistry
Volume 8, Issue 1, Pages 113-118

Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives

Keshav C. Patel and Himanshu D. Patel

Department of Chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, India

Received 10 May 2010; Accepted 20 July 2010

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A novel series of compounds containing coumarinyl sydnone derivatives from 4-methyl-7-hydroxy-8-nitro coumarin were synthesized. The formed compounds have been evaluated by physical methods (melting point, thin layer chromatography, elemental analysis) and by spectral data (IR, 1H-NMR & 13C NMR). The antimicrobial evaluation of the compounds showed that some of them revealed promising antimicrobial activity.