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E-Journal of Chemistry
Volume 8 (2011), Issue 1, Pages 59-62

Antifungal Activities of Ketoazomethines of Phenyl Glyoxal and p-Substituted Anilines

Vishnu Vats,1 R. K. Upadhyay,1 and Prathibha Sharma2

1Department of Chemistry, N.R.E.C College, Chaudhary Charan Singh University, Meerut, India
2Department of Plant Pathology, Indian Agricultural and Research Institute, New Delhi, India

Received 16 February 2010; Accepted 22 April 2010

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A new series of ketoazomethines were synthesized by condensation of phenyl glyoxal (prepared by partial oxidation of acetophenone) with various p-substituted anilines viz. p-Cl, p-Br, p-NO2, p-(C2H5)2N and p-CH3. These compounds were characterized by elemental analysis, IR and H1 NMR. The synthesized ketoazomethines were screened for their antifungal acsutivity against hazardous fungi namely Fusarium oxysporum, Alternaria brassicola, Sclerotium and Pythium.