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E-Journal of Chemistry
Volume 8 (2011), Issue 1, Pages 119-122

Microwave Assisted Synthesis and Antimicrobial Activities of Some 2-Amino-4-aryl-3-cyano-6-(4’-hydroxy phenyl)-pyridines

Priya Gothwal, Gunwanti Malhotra, and Y. K. Srivastava

Department of Chemistry, M.P. Govt. P.G. College, Chittorgarh-312001, India

Received 18 May 2010; Accepted 23 July 2010

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


4’-Hydroxy chalcones were treated with malononitrile in the presence of ammonium acetate under solventless microwave assisted condition to get 2-amino-4-aryl-3-cyano-6-(4’-hydroxy phenyl)-pyridines. The prepared compounds were screened for their antimicrobial activity; some of them have exhibited promising antimicrobial activity.