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E-Journal of Chemistry
Volume 9 (2012), Issue 1, Pages 425-429

Fast and Efficient Synthesis of 4-Arylidene-3-phenylisoxazol-5-ones

Maryam Mirzazadeh1 and Gholam Hossein Mahdavinia2

1Department of Chemistry, Firoozabad Branch, Islamic Azad University, Fars, Iran
2Department of Chemistry, Marvdasht Branch, Islamic Azad University, Fars, Iran

Received 2 July 2011; Accepted 27 August 2011

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A convenient and easy synthesis of 4-arylidene-3-phenylisoxazol-5-ones by the three-component reaction of hydroxylamine, ethyl benzoylacetate and aromatic aldehydes in the presence of DABCO in refluxing ethanol is reported.