Synthesis of Substituted 3,4-Dialkyl-2,6-Diaryl-Piperidin-4-ol Derivatives and Their Conformational Study
The synthesis of series of 3,4-dialkyl-2,6-diaryl-piperidin-4-ol derivatives (7-12) by reduction of cis-3-alkyl-2,6-diarylpiperidin-4-one (1-6) using Grignard reagent has been reported. The synthesized heterocycles have been characterized on basis of spectroscopic data and their conformation has also been discussed.
Spectra of 3,4-dialkyl-2,6-diaryl-piperidin-4-on (7-12).
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