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E-Journal of Chemistry
Volume 9, Issue 4, Pages 2128-2133

Design and Synthesis of Crown Ether Functionalized Imidazoles as a New type of Building Blocks

Key Laboratory Chemical Biology Hebei Province, Key Laboratory of Medical Chemistry and Molecular Diagnosis, Ministry of Education, College Chemistry and Environmental Science, Hebei University, Baoding 071002, China

Received 28 September 2011; Accepted 9 November 2011

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A simple, convenient and efficient synthesis for a series of crown ether functionalized imidazoles from benzo-15-crown-5 (B15C5), benzo-18-crown-6 (B18C6), imidazole (Im), 2-methylimidazole (mIm), benzimidazole (bIm) and 2-methyl benzimidazole (mbIm) is reported. All these compounds obtained were characterized by IR, 1H NMR, ESI-MS and elemental analysis.