Journal of Chemistry

Journal of Chemistry / 2012 / Article

Open Access

Volume 9 |Article ID 865414 | 6 pages | https://doi.org/10.1155/2012/865414

An Efficient Synthesis of Thiazolo and Thiadiazolo Quinoxaline Derivatives in Ionic Liquid

Received21 Jul 2011
Accepted05 Sep 2011

Abstract

A series of 3-substitutedphenyl-1-thia-tetrazopentaleno[1,2-b] naphthalene 4(a-d) and 2-substitutedphenyl-1-thia-pentazopentaleno[1,2-b] naphthalene 5(a-d) were synthesized via., the reaction of 2-aminothiazoles 2(a-d) and 2-aminothiadiazoles 3(a-d) with 2,3-dichloro quinoxaline 1 in ionic liquid without using any catalyst. This protocol has the advantages of easier workup, milder reaction conditions, high yields, and environmentally benign procedure over traditional methods. The synthesized compounds 4(a-d) and 5(a-d) tested for their anti-fungal activity and these compounds were characterized by IR, NMR and Mass spectral analysis.

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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