An Efficient One-Pot Three-Component Synthesis of Novel Sulfanyl Tetrazoles Using Ionic Liquids

Table 3

Synthesis of sulfanyl tetrazoles 4a–f and 6a–f in [Bmim]BF₄ ionic liquid.

Entry	R	R1	R2	Product	Time (h)^a	Yield (%)^b
1	—	H	H	4a	4	88
2	—	H	Cl	4b	4.5	85
3	—	Cl	Cl	4c	4.5	78
4	—	H	Br	4d	5	82
5	—	Br	Br	4e	5.5	75
6	—	OMe	H	4f	6	81
7	H	—	—	6a	3	90
8	4-Cl	—	—	6b	2	91
9	4-Br	—	—	6c	3	88
10	4-Me	—	—	6d	3.5	83
11	4-OMe	—	—	6e	4	86
12	4-NO2	—	—	6f	2.5	80

^aTime for total completion of the reaction.
^bIsolated yield.