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Journal of Chemistry
Volume 2013, Article ID 139561, 4 pages
Research Article

A Simple and Sensitive HPTLC Method for Simultaneous Determination of Metformin Hydrochloride and Sitagliptin Phosphate in Tablet Dosage Form

Department of Pharmaceutical Chemistry, K. B. Institute of Pharmaceutical Education and Research, Kadi Sarva Vishwavidyalaya, Gujarat, Gandhinagar 382023, India

Received 25 June 2012; Revised 17 September 2012; Accepted 20 September 2012

Academic Editor: Paraskevas D. Tzanavaras

Copyright © 2013 Darshana K. Modi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Martinfdale—the Complete Drug Reference, Pharmaceutical Press, London, UK, 2005.
  2. G. A. Herman, A. Bergman, F. Liu et al., “Pharmacokinetics and pharmacodynamic effects of the oral DPP-4 inhibitor sitagliptin in middle-aged obese subjects,” Journal of Clinical Pharmacology, vol. 46, no. 8, pp. 876–886, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. British Pharmacopoeia, vol. 1 of Controller of Her Majesty's Stationary Office, London, UK, 4th edition, 2008.
  4. Indian Pharmacopoeia, vol. 1, The Controller of Publications, New Delhi, India, 1996.
  5. United State Pharmacopoeia National Formulary, vol. 2, United States Pharmacopoeial Convention, Rockville, Md, USA, 2005.
  6. J. G. Swales, R. T. Gallagher, M. Denn, and R. M. Peter, “Simultaneous quantitation of metformin and sitagliptin from mouse and human dried blood spots using laser diode thermal desorption tandem mass spectrometry,” Journal of Pharmaceutical and Biomedical Analysis, vol. 55, no. 3, pp. 544–551, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Khan, D. Sahu, Y. P. Agrawal, N. Sabarwal, A. Jain, and A. K. Gupta, “Simultaneous estimation of metformin and sitagliptin in tablet dosage form,” Asian Journal of Biochemical and Pharmaceutical Research, vol. 1, pp. 352–358, 2011. View at Google Scholar
  8. R. I. El-Bagary, E. F. Elkady, and B. M. Ayoub, “Liquid chromatographic determination of sitagliptin either alone or in ternary mixture with metformin and sitagliptin degradation product,” Talanta, vol. 85, no. 1, pp. 673–680, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. ICH Harmonized Tripartite Guidelines on Validation of Analytical Procedures: Text and Methodology Q2 (R1), Current Step 4 Version, Geneva, Switzerland, 2005.